The COX18 antibody - middle region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Horse, Porcine, and Rabbit antigen. The COX18 antibody - middle region has been validated for the following applications: Western Blot.
Description
This is a rabbit polyclonal antibody against COX18. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c